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NhCPH: Normal Human Liver Plateable Hepatocytes
Isolated from whole human livers that are not suitable for liver transplantation. The cell composition consists of a homogenous population of hepatocytes which are characterized by viability, morphology, plating efficiency and various functional testing including multiple CYP450 basal and induction levels including CYP3A4, CYP2D6, CYP2C9, CYP1A2, and CYP2B6.
In addition, Novabiosis primary human hepatocytes will undergo an ECOD study for 7-HCG and 7-HCS formation, and finally each lot will be tested for its ability to maintain function for a minimum period of 5 days and will be reported on the quality control report delivered with each vial.
Cells per vial: 3m | Minimum 5M
Shipping Conditions: Dry Ice or LN2
Storage Conditions: LN2 Storage
Upon receipt, immediately transfer each cryovial into the vapor phase of a liquid nitrogen storage Dewar. Cells are viable for at least 2 years when stored under these conditions.
Donor Information Includes:
Age, sex, race, diabetic status, smoking history, alcohol use, and any co-morbidities.
Serology results include (positive or negative):
CMV, EBV HBV, HCV, HIV‐1, HIV‐2. Additional serology results may be provided upon request.
Culture results include:
Negative: Bacteria, Yeast, Mycoplasma and Fungi
Novabiosis Plateable Primary Human Hepatocytes can be used for induction, toxicity, drug metabolism, drug screening, drug transporter activity, drug-drug interaction, among other uses.
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